Ovulation Induction

What is Ovulation Induction?

This process uses hormonal therapy to stimulate a woman’s egg development and egg release, also known as ovulation. These medications are used typically in women who are unable to ovulate on their own or women who have irregular menstrual cycles. The main goal is to produce a single, healthy egg! The second use of this technique is to increase the number of eggs reaching maturity in a woman’s single cycle in order to increase chances of conception.

Additional Tests during Ovulation Induction

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Blood Work (BW)

One of the first steps in determining if a woman is in need of ovulation induction is blood work. This is done to measure hormone levels. The blood test is usually done on the second or third day of a woman’s cycle, and is used to evaluate egg supply and ovarian function.

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Transvaginal Ultrasound (ULS)

A Transvaginal Ultrasound is the act of applying an ultrasound transducer into the vagina to visualize and get images of organs within the pelvic cavity. This is typically done 3-4 times during Ovulation Induction to check for follicle growth and the thickening of the wombs lining throughout the process.

Medications

Clomiphene Citrate (Clomid)

Clomid is an oral medication that is used to induce ovulation primarily by blocking estrogen receptors. This is an artificial and-estrogen approach that makes your body believe that your estrogen levels are low, which causes it to begin stimulating the production of more follicle hormones (FSH). This is also considered superovulation, the release of multiple eggs in a given menstrual cycle.

Monitoring:

Some monitoring is necessary while taking Clomiphene Citrate (Clomid). This may include Transvaginal Ultrasounds, Blood Work to determine estrogen levels. Clomid is often prescribed with Intrauterine Insemination (IUI).

Follicle Stimulating Hormone (Follistim / Gonal-F)

Follicle Stimulating Hormone (FSH) medications are used to stimulate the development of multiple eggs in a woman during the Ovulation Induction Cycle. Because of the numerous responses we see patient to patient, no fixed dosage can be reccommended. Dr. Dipaola will ensure you that the dosage prescribed is what works best for you and your situation. FSH is available only in an injectable form. Because this medication is self-administered in the comfort of your own home, our nursing staff will set up a time to meet with you for a teach either in person or via video conference call. The goal will be to teach you how to administer the drug. This will ensure the safety of the situation and give you the opportunity to ask any questions you may have.

Monitoring:

In addition to the Teach, Transvaginal Ultrasounds and Blood Work are also done for this medication to assess the ovarian response. Monitoring in this situation reduces the risk of possible complications.

Human Chorionic Gondatropin (Pregnyl, Ovidrel):

Human Chorionic Gonadotropin (HCG) is a natural hormone that helps with the final maturation of a woman’s eggs and triggers the ovaries to release the mature eggs (ovulation). It is also used to stimulate the corpus luteum (a mass of cells that forms in an ovary and is responsible for the production of the hormone progesterone during early pregnancy) to produce and discharge progesterone to prepare the lining of the uterus for the fertilized egg. Ovulation typically occurs about 36 hours after the HCG injection is given.

Monitoring:

similar to other drugs used for Ovulation Induction, this is monitored with Transvaginal Ultrasounds and Blood work.

Leuprolide (Lupron)

Lurpon is used to suppress the brain’s secretion of the leutinizing hormone (LH) (a hormone secreted by the anterior pituitary gland that stimulates ovulation in females and the synthesis of androgen in males) and follicle stimulating hormone (FSH). It is used most in preperation for cycles of treatment with Ovulation Induction drugs. Lupron enables the ovaries to respond with the attracting of multiple follicles. in some cases it is possible to override the selection of an indicidual follicle. This medication is also responsible for preventing premature ovulation by stopping LH release.

Similar to FSH, this drug is a self-administered injectable. Our nursing staff will set up a time to meet with you for a teach either in person or via video conference call. The goal will be to teach you how to administer the drug. This will ensure the safety of the situation and give you the opportunity to ask any questions you may have.

Monitoring:

In order to be sure if Lupron is doing it’s job appropriately, Transvaginal Ultrasounds are done throughout the process as well as Blood Work to check estrogen levels.

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630 Frankhauser Rd. Williamsville, NY 14221

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